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22 April 2024: Clinical Research

Predicting Acute Cardiovascular Complications in COVID-19: Insights from a Specialized Cardiac Referral Department

Michał Machowski 1ABCDEF , Aisha Ou-Pokrzewińska 1BCDEF , Katarzyna Perzanowska-Brzeszkiewicz 1BCDEF , Magdalena Gałecka-Nowak 1BDE , Szymon Pacho 1BDE , Mateusz Jermakow 1BCDE* , Agnieszka Wójcik 1BDE , Milena Zoruk 1BDE , Andrzej Pruszczyk 1BDE , Karol Deutsch 1BDE , Marek Roik 1BDE , Andrzej Łabyk 1BDE , Piotr Palczewski 2ABDEF , Piotr Pruszczyk 1ABCDEF

DOI: 10.12659/MSM.942612

Med Sci Monit 2024; 30:e942612

Table 4 Optimal cut-off points for the diagnosis of acute cardiovascular diseases.

Parameter [unit]Optimal cut-off pointAUC (95% CI)Sensitivity (%)Specifity (%)PPV (%)NPV (%)P-value
D-dimer [ng/ml]4968.50.850 (0.765; 0.935)69.496.280.693.3
NT-proBNP [pg/ml]8970.00.692 (0.502; 0.883)54.586.525.095.80.004
Left ventricle ejection fraction [%]33.50.948 (0.899; 0.996)86.791.261.997.6
AUC – area under curve; CI – confidence interval; LVEF – left ventricle ejection fraction; PPV – positive predictive value; NPV – negative predictive value; ACS – acute coronary syndrome; AMyo – acute myocarditis; APE – acute pulmonary embolism; CAD – coronary artery disease; CHF – congestive heart failure; CRP – C-reactive protein; MEWS – Modified Early Warning Score.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750